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Before we dive into the list of GHK-Cu contraindications, let's quickly align on what GHK-Cu is

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years

The ingestion of a high-calorie diet or the consumption of substantial amounts of alcohol has been demonstrated to promote DNL through the activation of two transcription factors: carbohydrate response element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c)

However, there is no scientific evidence supporting B12 supplementation for direct fat loss in individuals with normal B12 levels